Topley M, Novick A C, Montie J E
J Urol. 1984 Jun;131(6):1050-2. doi: 10.1016/s0022-5347(17)50802-2.
From 1956 to 1980 partial nephrectomy was done on 23 patients with localized renal carcinoma occurring bilaterally or in a solitary functioning kidney. The mean postoperative followup was 5.4 years, and the 5-year patient survival rates considering death of renal cancer only or of any cause were 70.2 and 59.6 per cent, respectively. Survival was diminished in patients with bilateral asynchronous renal carcinoma. Renal carcinoma recurred postoperatively in 6 patients (26 per cent), including 3 (13 per cent) with local recurrence in the renal remnant. Currently, 12 patients (52 per cent) are alive with stable function and no evidence of malignancy. These long-term data support the efficacy of partial nephrectomy for selected patients with renal carcinoma.
1956年至1980年期间,对23例双侧发生或单侧孤立功能性肾出现局限性肾癌的患者实施了部分肾切除术。术后平均随访时间为5.4年,仅考虑死于肾癌或任何原因的5年患者生存率分别为70.2%和59.6%。双侧异步肾癌患者的生存率降低。6例患者(26%)术后出现肾癌复发,其中3例(13%)在肾残余局部复发。目前,12例患者(52%)存活,肾功能稳定,无恶性肿瘤迹象。这些长期数据支持了部分肾切除术对特定肾癌患者的疗效。