Lüders D, Phieler H
Monatsschr Kinderheilkd. 1984 Apr;132(4):217-21.
The toxic shock syndrome in a 14-year old girl is described. This syndrome occurs most frequently - but not exclusively - in the teens and young women during the first days of menstruation, if tampons are used. The patients are acutely ill with high fever, diarrhea and/or vomiting, with a rash, with loss of consciousness, and signs of shock (occasionally shock lung syndrome and renal insufficiency). During convalescence desquamation of hands and feet shows up. Patients with much less severe symptoms have been seen. The primary lesion is a local infection (e.g. vaginitis) with staphylococcus aureus, the symptoms being caused by staphylococcal toxins. Early recognition and immediate therapy are important for a better prognosis. The therapy consists of removal of the tampon, i.v. fluids including albumin, and the administration of a beta-lactamase-resistant antibiotic.
描述了一名14岁女孩的中毒性休克综合征。这种综合征最常——但并非仅——发生在青少年和年轻女性月经来潮的最初几天，若使用卫生棉条的话。患者病情急重，伴有高热、腹泻和/或呕吐、皮疹、意识丧失及休克体征（偶尔出现休克肺综合征和肾功能不全）。恢复期会出现手足脱皮。也见过症状轻得多的患者。原发性损害是由金黄色葡萄球菌引起的局部感染（如阴道炎），症状由葡萄球菌毒素所致。早期识别和立即治疗对改善预后很重要。治疗包括取出卫生棉条、静脉输注包括白蛋白在内的液体，以及给予一种对β-内酰胺酶耐药的抗生素。
