Nicholson H D, Swann R W, Burford G D, Wathes D C, Porter D G, Pickering B T
Regul Pept. 1984 Mar;8(2):141-6. doi: 10.1016/0167-0115(84)90169-1.
Oxytocin, vasopressin and neurophysin-like immunoreactivity have been identified and measured by radioimmunoassay in extracts of human and rat testis and human fetal adrenal tissue. The authenticity of these polypeptides has been confirmed by their behaviour on high performance liquid chromatography. The concentrations of the hormone were too great to be explained by known circulating levels of the polypeptides, and their presence in steroid secreting organs suggests a possible role for them in steroidogenesis. The peptides may be taken up and concentrated by the tissues but the co-localisation of neurophysins with the hormones points towards local synthesis.
通过放射免疫分析法已在人和大鼠睾丸提取物以及人胎儿肾上腺组织中鉴定并测量了催产素、加压素和神经垂体素样免疫反应性。这些多肽的真实性已通过它们在高效液相色谱上的行为得到证实。这些激素的浓度过高，无法用已知的多肽循环水平来解释，并且它们在类固醇分泌器官中的存在表明它们在类固醇生成中可能发挥作用。这些肽可能被组织摄取并浓缩，但神经垂体素与激素的共定位表明是局部合成。
