间歇性化疗治疗淀粉样变性的客观缓解情况。
Objective response in amyloidosis treated with intermittent chemotherapy.
作者信息
Farhangi M, Thakur V M, Durham J B
出版信息
South Med J. 1984 Jun;77(6):775-7. doi: 10.1097/00007611-198406000-00031.
Abstract
A 37-year-old woman with amyloidosis derived from light chain immunoglobulin had hepatosplenomegaly, elevated serum alkaline phosphatase values, and progressively destructive bony lesions. A 44-month intermittent course of chemotherapy with melphalan and prednisone resulted in regression, confirming the occasional efficacy of cytotoxic chemotherapy in this disease.
摘要
一名患有轻链免疫球蛋白源性淀粉样变性的37岁女性出现肝脾肿大、血清碱性磷酸酶值升高以及进行性破坏性骨病变。采用美法仑和泼尼松进行了为期44个月的间歇性化疗，结果病情缓解，证实了细胞毒性化疗在这种疾病中的偶尔疗效。
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