Logan L L, Goodwin J T, Tembely S, Craig T M
Trop Anim Health Prod. 1984 Feb;16(1):1-12. doi: 10.1007/BF02248921.
A study was initiated to evaluate two trypanocidal drugs, the prophylactic isometamidium chloride (Trypamidium) and the curative diminazene aceturate (Berenil) as to their potential for long-term maintenance of zebu cattle in a tsetse infested area of Mali. Trypamidium was administered quarterly and Berenil was administered only as animals were found to be positive for trypanosomes. During the 21-month study trypanosomiasis was the most frequently encountered disease in the cattle in the Berenil treatment group with an average of 5.5 reinfections. The predominant trypanosome species encountered was Trypanosoma vivax and the most important vector was Glossina palpalis gambiensis. The results indicate that, even though the direct costs for drugs under the two maintenance regimens were almost identical, the use of Trypamidium resulted in a significantly greater annual weight gain, prevented death loss due to trypanosomiasis and resulted in a herd with a greater market value.
