Rolny P, Goobar J, Zettergren L
Acta Med Scand. 1984;215(4):391-5. doi: 10.1111/j.0954-6820.1984.tb05024.x.
Two patients are described who suffered from both HBsAg-negative chronic active hepatitis and mixed connective tissue disease syndrome. The diagnosis of liver disease was made prior to the diagnosis of collagenosis in one of the patients, whereas the opposite was the case in the other. In spite of the fact that symptoms and laboratory data suggesting both diagnoses were present from the moment of presentation, there was a considerable delay in establishing the second diagnosis in both patients. To our knowledge, this is the first report on an association between chronic active hepatitis and mixed connective tissue disease syndrome. It illustrates the difficulties when diagnosing overlap conditions.
本文描述了两名同时患有乙肝表面抗原阴性慢性活动性肝炎和混合性结缔组织病综合征的患者。其中一名患者在诊断胶原病之前就已确诊肝病，而另一名患者情况则相反。尽管从就诊时起就存在提示两种诊断的症状和实验室数据，但两名患者在确诊第二种疾病时均出现了相当长的延迟。据我们所知，这是关于慢性活动性肝炎与混合性结缔组织病综合征之间关联的首例报告。它说明了诊断重叠病症时的困难。
