Cockerham C C, Weir B S
Biometrics. 1984 Mar;40(1):157-64.
We consider covariances of all parent and first-generation relatives from outcrossing or self-fertilization in a parent population that is in equilibrium with respect to these processes. The results, which are for any number of alleles and loci with additive and dominance effects, are phrased in terms of six quadratic genetic components whose coefficients are given by descent measures for equilibrium populations. Because of the variation in the inbreeding coefficients for this system of mating, the expressions include joint contributions of loci to the variances and covariances of relatives. By inclusion of the full complement of relatives, all quadratic components can be estimated. The findings of Ghai (1982, Biometrics 38, 87-92) for compound functions of the covariances with two alleles at a single locus are analyzed in terms of the more general model.
我们考虑了在一个关于这些过程处于平衡状态的亲本群体中，异交或自交产生的所有亲本和第一代亲属的协方差。结果适用于任意数量具有加性和显性效应的等位基因和基因座，用六个二次遗传成分来表述，其系数由平衡群体的亲缘系数给出。由于这种交配系统中近交系数的变化，这些表达式包括了基因座对亲属方差和协方差的联合贡献。通过纳入亲属的完整集合，可以估计所有的二次成分。根据更一般的模型分析了Ghai（1982年，《生物统计学》38卷，87 - 92页）关于单个基因座上两个等位基因协方差的复合函数的研究结果。
