Burton T C, Lambert R W
Ophthalmology. 1978 Jun;85(6):619-25. doi: 10.1016/s0161-6420(78)35636-0.
By multiple regression analysis we have identified 26 out of 200 observations which significantly affect the visual acuity following retinal detachment surgery. In addition, we have developed a highly significant mathematical model, which is able to predict in rather broad ranges of visual acuity to approximately 67% accuracy. There is still a large percentage of patients for whom we cannot account for the variability in final vision, a problem requiring future investigation. Potentially important factors which were not analyzed in this study include duration of macular detachment, afferent pupil defect, drainage of subretinal fluid, extent of the scleral-buckling procedure, and postoperative follow-up longer than six months. While most of the variables are fixed and cannot be alterd, such as age, senile cataract, and refractive error, improved knowledge of influential factors may allow us to manipulate some of them and provide mechanisms for improving results in recovery or maintenance of macular function after retinal detachment surgery.
通过多元回归分析,我们在200例观察对象中确定了26例对视网膜脱离手术后视力有显著影响的病例。此外,我们还建立了一个高度显著的数学模型,该模型能够在相当广泛的视力范围内进行预测,准确率约为67%。仍有很大比例的患者,我们无法解释其最终视力的变异性,这是一个需要未来研究的问题。本研究未分析的潜在重要因素包括黄斑脱离的持续时间、传入性瞳孔缺陷、视网膜下液引流、巩膜扣带手术的范围以及术后超过六个月的随访。虽然大多数变量是固定的,无法改变,如年龄、老年性白内障和屈光不正,但对影响因素的深入了解可能使我们能够控制其中一些因素,并为改善视网膜脱离手术后黄斑功能恢复或维持的结果提供机制。