Shaw E L, Rao G N, Arthur E J, Aquavella J V
Ophthalmology. 1978 Jun;85(6):640-9. doi: 10.1016/s0161-6420(78)35634-7.
With recent advances in our knowledge of corneal physiology, coupled with the development and increasing availability of the specular microscope as a clinical instrument, valid observations relating the morphologic appearance of the corneal endothelium to its functional capacity are within our reach. Manual methods of data analysis are cumbersome, time consuming, and associated with human error and investigator bias. The Omnicon pattern analysis system lends itself to objective analysis of morphologic features, offers the possibility of quantifying the data obtained and, hopefully, will lead to a better understanding of the many aspects of endothelial cell morphology which, in total, relate to the functional reserve of a given cornea.
随着我们对角膜生理学认识的最新进展，再加上作为临床仪器的镜面显微镜的开发及其越来越广泛的应用，有关角膜内皮细胞形态外观与其功能能力之间关系的有效观察已触手可及。手动数据分析方法既繁琐又耗时，还存在人为误差和研究者偏差。Omnicon模式分析系统有助于对形态特征进行客观分析，提供了对所获数据进行量化的可能性，并且有望使我们更好地理解内皮细胞形态学的诸多方面，而这些方面总体上与特定角膜的功能储备相关。
