O'Shea J D, Wright P J
Cell Tissue Res. 1984;236(2):477-85. doi: 10.1007/BF00214253.
Involution and regeneration of the endometrium after parturition in the ewe, were studied by light- and electron microscopy. The luminal epithelium in intercaruncular regions of the endometrium remained intact at all stages, but degeneration and death of many glandular epithelial cells were observed on the day after parturition. Glandular regeneration had commenced by 8 d post partum, and the glands were substantially regenerated by 15 d. Caruncular epithelial cells on the maternal side of the placentomes, between the bases of the maternal septa, persisted during the period of degeneration of the foetal and maternal tissues of the placentomes. Epithelial cells from this source contributed to the regeneration of the caruncular epithelium following shedding of plaques of degenerate placental tissue from the caruncles, which commenced after 8 d and was completed before 31 d. Thus, ingrowth of epithelium from the edges of the caruncles, as previously proposed, was not the sole source of new caruncular epithelium. The additional source of regenerating epithelium identified here may account for the rapidity with which epithelium appears in the centres of some caruncles, several millimetres in diameter, during endometrial regeneration. However, in some caruncles, regeneration of the epithelium was not completed until after 31 d post partum.
通过光学显微镜和电子显微镜对母羊产后子宫内膜的 involution 和再生进行了研究。子宫内膜肉阜间区域的腔上皮在所有阶段均保持完整，但在产后第1天观察到许多腺上皮细胞发生退化和死亡。产后8天开始腺再生，到15天时腺体基本再生完成。胎盘母体隔基部之间胎盘母体侧的肉阜上皮细胞，在胎盘胎儿和母体组织退化期间持续存在。在8天后开始并在31天前完成的肉阜退化胎盘组织斑块脱落之后，来自该来源的上皮细胞有助于肉阜上皮的再生。因此，如先前提出的那样，来自肉阜边缘的上皮向内生长并不是新肉阜上皮的唯一来源。此处确定的再生上皮的额外来源可能解释了在子宫内膜再生过程中，上皮在一些直径达数毫米的肉阜中心出现的速度。然而，在一些肉阜中，上皮再生直到产后31天才完成。
