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血液透析患者四种家用血糖监测方法的准确性

Accuracy of four methods of home blood glucose monitoring in hemodialysis patients.

作者信息

Vanden Bosch M A, Hyneck M L

出版信息

Clin Pharm. 1984 May-Jun;3(3):291-4.

PMID:6734091
Abstract

The accuracy of four techniques of home blood glucose monitoring in hemodialysis patients was compared. Arterial-venous blood samples were collected from 23 patients undergoing hemodialysis and analyzed for serum glucose concentrations using an automated laboratory method. Capillary-blood glucose concentrations were also determined in each patient by visual readings of the Chemstrip bG and Dextrostix reagent strips and by reflectometer readings of the StatTek Glucose and Dextrostix reagent strips. Readings of glucose concentration obtained by each of the four techniques were compared with laboratory-determined values, and the true and absolute deviations in these values for each technique were recorded. The effect of patient hematocrit on deviations in glucose concentration readings was evaluated by analysis of variance. The mean glucose concentration readings obtained using the visual and reflectometer (Dextrometer) readings of Dextrostix were substantially less accurate than the other two techniques when compared with serum glucose concentrations determined by the laboratory. The StatTek technique gave the smallest mean absolute deviation from laboratory-determined values. No correlation was found between the patient's hematocrit and either the true or absolute deviations in glucose concentrations. The Chemstrip bG and StatTek techniques are reasonably accurate methods for home monitoring of blood glucose concentrations in diabetic patients undergoing hemodialysis.

摘要

比较了四种家庭血糖监测技术在血液透析患者中的准确性。从23例接受血液透析的患者中采集动静脉血样,采用自动化实验室方法分析血清葡萄糖浓度。还通过Chemstrip bG和Dextrostix试纸条的目视读数以及StatTek葡萄糖和Dextrostix试纸条的反射仪读数来测定每位患者的毛细血管血糖浓度。将四种技术各自获得的葡萄糖浓度读数与实验室测定值进行比较,并记录每种技术这些值的真实偏差和绝对偏差。通过方差分析评估患者血细胞比容对葡萄糖浓度读数偏差的影响。与实验室测定的血清葡萄糖浓度相比,使用Dextrostix的目视和反射仪(Dextrometer)读数获得的平均葡萄糖浓度读数的准确性明显低于其他两种技术。StatTek技术与实验室测定值的平均绝对偏差最小。未发现患者血细胞比容与葡萄糖浓度的真实偏差或绝对偏差之间存在相关性。Chemstrip bG和StatTek技术是对接受血液透析的糖尿病患者进行家庭血糖浓度监测的合理准确方法。

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