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评估儿童用儿科制剂口味的方法:面部表情愉悦度法与患者自身自发语言判断的比较

Methods for evaluating the taste of paediatric formulations in children: a comparison between the facial hedonic method and the patients' own spontaneous verbal judgement.

作者信息

Sjövall J, Fogh A, Huitfeldt B, Karlsson G, Nylén O

出版信息

Eur J Pediatr. 1984 Feb;141(4):243-7. doi: 10.1007/BF00572770.

DOI:10.1007/BF00572770
PMID:6734676
Abstract

The aim of the study was to evaluate two essentially different methods of assessing differences in children's taste preferences with regard to five different paediatric penicillin formulations. The study was performed with a parallel group design comparing five groups. A taste evaluation was recorded in 103 children with upper respiratory tract infections after a single therapeutic test dose. First the patient's own spontaneous verbal judgement was recorded then a judgement was arrived at using a hedonic scale of facial expressions. Both judgements were passed immediately and also 3-4 minutes after the test dose. In the children who were 6 years of age or younger, a better discrimination of taste differences between formulations was achieved by using the patients' own spontaneous verbal judgements instead of the facial hedonic method. Both methods seem appropriate in older children, but the hedonic scale is preferable since its use implies a more standardised procedure.

摘要

该研究的目的是评估两种本质上不同的方法,以评估儿童对五种不同儿科青霉素制剂的口味偏好差异。该研究采用平行组设计,比较了五组。在103名上呼吸道感染儿童单次治疗测试剂量后记录了口味评估。首先记录患者自己的自发口头判断,然后使用面部表情的享乐量表得出判断。两种判断都在给药后立即进行,也在给药后3-4分钟进行。在6岁及以下的儿童中,通过使用患者自己的自发口头判断而不是面部享乐方法,能更好地区分制剂之间的口味差异。两种方法在年龄较大的儿童中似乎都适用,但享乐量表更可取,因为使用它意味着程序更标准化。

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Evaluation of patient-reported outcome measurements as a reliable tool to measure acceptability of the taste of paediatric medicines in an inpatient paediatric population.评估患者报告的结局测量指标作为衡量住院儿科患者群体中儿科药物口味可接受性的可靠工具。
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