Redding J M, Patiño R, Schreck C B
Gen Comp Endocrinol. 1984 Jun;54(3):433-43. doi: 10.1016/0016-6480(84)90159-x.
The metabolic clearance rate of corticosteroids determined after a single injection of [3H]cortisol was higher in fish acclimated to seawater (SW) than in those acclimated to fresh water (FW). Uptake and retention of corticosteroids in liver, gill filaments, and gall bladder bile were greater in SW than in FW fish. The stress of long-term (5 days), but not short-term (12 hr), continuous confinement apparently increased the clearance rate of corticosteroids in both FW and SW fish. Chronic, but not acute, administration of exogenous cortisol, yielding cortisol titers close to the physiological range, appeared to increase the clearance rate of corticosteroids in FW fish.
单次注射[3H]皮质醇后测定的皮质类固醇代谢清除率，在适应海水（SW）的鱼类中高于适应淡水（FW）的鱼类。SW鱼类肝脏、鳃丝和胆囊胆汁中皮质类固醇的摄取和保留量均高于FW鱼类。长期（5天）而非短期（12小时）连续禁闭的应激，显然增加了FW和SW鱼类中皮质类固醇的清除率。慢性而非急性给予外源性皮质醇，使皮质醇水平接近生理范围，似乎增加了FW鱼类中皮质类固醇的清除率。
