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72小时睡眠剥夺对尿皮质醇及代谢指标的影响。

Effects of 72 hour sleep deprivation on urinary cortisol and indices of metabolism.

作者信息

Kant G J, Genser S G, Thorne D R, Pfalser J L, Mougey E H

出版信息

Sleep. 1984;7(2):142-6. doi: 10.1093/sleep/7.2.142.

DOI:10.1093/sleep/7.2.142
PMID:6740058
Abstract

Cortisol, urea, glucose, electrolytes, and other compounds were measured in five consecutive 24 h urine collections during a 72 h sleep deprivation study in six young men. Urine was collected during a 24 h predeprivation day, 3 days of sleep deprivation, and a recovery day. Whereas urinary cortisol decreased only slightly, marked changes in other urinary constituents were observed. During sleep deprivation, urinary urea rose markedly, glucose decreased, and urinary electrolytes decreased. These data indicate that sleep deprivation under ad lib food and water conditions can cause disturbances in normal metabolism.

摘要

在一项针对六名年轻男性的72小时睡眠剥夺研究中,连续五次收集他们24小时的尿液,以测量皮质醇、尿素、葡萄糖、电解质及其他化合物。尿液收集时间为剥夺睡眠前的24小时、睡眠剥夺的3天以及恢复日。虽然尿皮质醇仅略有下降,但其他尿成分却出现了显著变化。在睡眠剥夺期间,尿尿素显著上升,葡萄糖下降,尿电解质减少。这些数据表明,在随意饮食和饮水的条件下,睡眠剥夺会导致正常代谢紊乱。

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