Baumann H, Schneider H, Grob P J, Huch R, Huch A
Schweiz Med Wochenschr. 1984 Jun 2;114(22):783-7.
Passive and active immunization prevent materno-fetal and postnatal hepatitis B-virus infection. Precondition for interruption of perinatal transmission is knowledge of the mothers' hepatitis B markers before delivery. In switzerland the prevalence of chronic asymptomatic pregnant HBsAG carriers is not known. From February to December 1983 all pregnant women at the Obstetric Clinic, University Hospital of Zurich were screened for HBsAG. 30 out of 2550 women were HBsAG positive (1.2%); the prevalence among Swiss women is 0.5%, and among immigrants 1.9%. It is suggested that screening for HBsAG be confined to pregnant women who belong to a risk group and to immigrants, and that all children born of HBsAG positive mothers be immunized actively and passively regardless of the presence of HBeAG and/or anti-HBe.
被动免疫和主动免疫可预防母婴及产后乙型肝炎病毒感染。阻断围产期传播的前提是在分娩前了解母亲的乙肝标志物情况。在瑞士，慢性无症状孕妇HBsAG携带者的患病率尚不清楚。1983年2月至12月，苏黎世大学医院产科诊所对所有孕妇进行了HBsAG筛查。2550名女性中有30名HBsAG呈阳性（1.2%）；瑞士女性中的患病率为0.5%，移民中的患病率为1.9%。建议将HBsAG筛查局限于高危组孕妇和移民，并且所有HBsAG阳性母亲所生的孩子无论是否存在HBeAG和/或抗-HBe均应进行主动免疫和被动免疫。
