Taylor S, Achola K, Smith G
Anaesthesia. 1984 Jun;39(6):520-3. doi: 10.1111/j.1365-2044.1984.tb07353.x.
Plasma catecholamine concentrations were measured in 19 patients allocated randomly to receive submucous infiltration with 4 ml of either 0.5% lignocaine with adrenaline 1:200 000 or prilocaine 0.5% with octapressin 0.03 iu per ml. Venous blood samples were obtained before and at 2, 5, and 10 minutes following infiltration. Plasma adrenaline increased from 0.35 to 1.72 p mol/ml at 2 minutes infiltration with the former solution whilst there was little change in plasma noradrenaline concentration. No similar peak in adrenaline concentration occurred after infiltration with prilocaine/ octapressin solutions but with both solutions there was a small increase in plasma noradrenaline and adrenaline concentrations 10 minutes after infiltration, at the time of surgical stimulation.
对19例随机分配接受黏膜下浸润的患者进行血浆儿茶酚胺浓度测定，这些患者分别接受4毫升含1:200 000肾上腺素的0.5%利多卡因或每毫升含0.03国际单位奥曲肽的0.5%丙胺卡因。在浸润前以及浸润后2分钟、5分钟和10分钟采集静脉血样。使用前一种溶液浸润2分钟时，血浆肾上腺素从0.35皮摩尔/毫升升至1.72皮摩尔/毫升，而血浆去甲肾上腺素浓度几乎没有变化。使用丙胺卡因/奥曲肽溶液浸润后，肾上腺素浓度没有出现类似的峰值，但在手术刺激时，即浸润10分钟后，两种溶液都使血浆去甲肾上腺素和肾上腺素浓度略有升高。
