Jastrzebski G B, Hoyt C S, Marg E
Arch Ophthalmol. 1984 Jul;102(7):1030-4. doi: 10.1001/archopht.1984.01040030832027.
In the SPE model we propose, sensitivity (S) to deprivation results in changes that may be either plastic (P) (permanent) or elastic (E) (temporary). The effects of various levels (hours per day) of monocular occlusion in amblyopic children are measured as the change in visual acuity in each eye. At the patching level extremes (12 or more hours per day, zero hours per day) the effects on visual acuity in the two eyes are reciprocal, but nearly equal (symmetrical). At intermediate levels of occlusion, the asymmetries in effects necessary for successful occlusion can be demonstrated. Additional measurements of SPE parameters in children may allow for the determination of occlusion dose response whereby the risks of occlusion amblyopia and interference with binocularity may be avoided.
在我们提出的SPE模型中，对剥夺的敏感性（S）会导致可能是可塑性（P）（永久性）或弹性（E）（暂时性）的变化。对弱视儿童进行不同程度（每天小时数）的单眼遮盖，其效果通过每只眼睛视力的变化来衡量。在遮盖程度的极端情况（每天12小时或更长时间，每天0小时）下，对双眼视力的影响是相互的，但几乎相等（对称）。在中等遮盖水平下，可以证明成功遮盖所需的效果不对称性。对儿童的SPE参数进行额外测量，可能有助于确定遮盖剂量反应，从而避免遮盖性弱视和双眼视觉干扰的风险。
