Kozuka S, Hachisuka K
Hum Pathol. 1984 Aug;15(8):779-84. doi: 10.1016/s0046-8177(84)80170-7.
The incidence by age and sex of intestinal metaplasia, focal mucosal hyperplasia, Rokitansky-Aschoff sinuses, and mucosal atrophy was determined histologically for 500 gallbladders from patients who had undergone cholecystectomy. All intestinal metaplastic changes increased steadily with age and were more frequent in female than in male patients younger than 70 years of age. Focal mucosal hyperplasia was often associated with mucous gland hyperplasia in elderly patients, particularly women.
通过组织学方法确定了500例接受胆囊切除术患者胆囊的肠化生、局灶性黏膜增生、罗-阿窦及黏膜萎缩的年龄和性别发病率。所有肠化生改变均随年龄稳步增加，在70岁以下的患者中，女性比男性更常见。局灶性黏膜增生在老年患者，尤其是老年女性中常与黏液腺增生相关。
