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与人类癌症相关的暴露因素。

Exposures associated with cancer in humans.

作者信息

Tomatis L

出版信息

J Cancer Res Clin Oncol. 1984;108(1):6-10. doi: 10.1007/BF00390967.

DOI:10.1007/BF00390967
PMID:6746717
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12252914/
Abstract

The IARC programme on the evaluation of the risk of chemicals to humans was initiated in the late 1960s in response to the request made to the Agency for information on environmental carcinogens. The programme, which has been implemented with the advice and the collaboration of a large number of international experts, is focused on the production of monographs on individual chemicals, groups of chemicals or complex exposures. The programme will shortly include also the evaluation of risks related to some of the most widely spread cultural habits. It has been, and still is, the policy of the programme to consider only published information in relation to biological data relevant to the evaluation of carcinogenic risks. One of the main limitations with regard to the possibility of accurately evaluating cancer risks was shown to be the shortage of information on the level of exposure to carcinogenic risk factors. To overcome such limitations it would appear that a close and continuous collaboration between experimentalists and epidemiologists be maintained.

摘要

国际癌症研究机构(IARC)关于评估化学物质对人类风险的项目始于20世纪60年代末,以回应向该机构索取环境致癌物信息的请求。该项目在众多国际专家的建议和合作下实施,专注于编写关于单个化学物质、化学物质组或复杂暴露情况的专论。该项目不久还将包括对一些传播最广泛的文化习惯相关风险的评估。只考虑与致癌风险评估相关的生物学数据的已发表信息一直是且仍然是该项目的政策。事实表明,准确评估癌症风险可能性的主要限制之一是致癌风险因素暴露水平信息的短缺。为克服这些限制,实验人员和流行病学家之间似乎应保持密切且持续的合作。

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本文引用的文献

1
Chemicals, industrial processes and industries associated with cancer in humans.与人类癌症相关的化学物质、工业过程和产业。
IARC Monogr Eval Carcinog Risk Chem Hum Suppl. 1982 Oct(4):7-24.
2
Practical limitations of epidemiologic methods.流行病学方法的实际局限性。
Environ Health Perspect. 1983 Oct;52:3-8. doi: 10.1289/ehp.83523.
3
Letter: International Agency for Research on Cancer (IARC) monographs on the evaluation of carcinogenic risk of chemicals to man: "Relevance of data on mutagenicity".信函:国际癌症研究机构(IARC)关于化学物质对人类致癌风险评估的专论:“致突变性数据的相关性”
Mutat Res. 1975 Jun;31(3):210.
4
Evaluation of the carcinogenicity of chemicals: a review of the Monograph Program of the International Agency for Research on Cancer (1971 to 1977).化学品致癌性评估:国际癌症研究机构专论项目(1971年至1977年)综述
Cancer Res. 1978 Apr;38(4):877-85.
5
Chemicals and industrial processes associated with cancer in humans. IARC Monographs, Volumes 1 to 20.与人类癌症相关的化学物质和工业过程。《国际癌症研究机构专论》,第1至20卷。
IARC Monogr Eval Carcinog Risk Chem Hum Suppl. 1979 Sep(1):1-71.