Tomatis L
J Cancer Res Clin Oncol. 1984;108(1):6-10. doi: 10.1007/BF00390967.
The IARC programme on the evaluation of the risk of chemicals to humans was initiated in the late 1960s in response to the request made to the Agency for information on environmental carcinogens. The programme, which has been implemented with the advice and the collaboration of a large number of international experts, is focused on the production of monographs on individual chemicals, groups of chemicals or complex exposures. The programme will shortly include also the evaluation of risks related to some of the most widely spread cultural habits. It has been, and still is, the policy of the programme to consider only published information in relation to biological data relevant to the evaluation of carcinogenic risks. One of the main limitations with regard to the possibility of accurately evaluating cancer risks was shown to be the shortage of information on the level of exposure to carcinogenic risk factors. To overcome such limitations it would appear that a close and continuous collaboration between experimentalists and epidemiologists be maintained.
国际癌症研究机构(IARC)关于评估化学物质对人类风险的项目始于20世纪60年代末,以回应向该机构索取环境致癌物信息的请求。该项目在众多国际专家的建议和合作下实施,专注于编写关于单个化学物质、化学物质组或复杂暴露情况的专论。该项目不久还将包括对一些传播最广泛的文化习惯相关风险的评估。只考虑与致癌风险评估相关的生物学数据的已发表信息一直是且仍然是该项目的政策。事实表明,准确评估癌症风险可能性的主要限制之一是致癌风险因素暴露水平信息的短缺。为克服这些限制,实验人员和流行病学家之间似乎应保持密切且持续的合作。