Alho H, Koistinaho J, Kovanen V, Suominen H, Hervonen A
J Auton Nerv Syst. 1984 Apr;10(2):181-91. doi: 10.1016/0165-1838(84)90056-0.
The effect of daily physical training for 24 months on the sympathetic neurons, adrenal gland, extra-adrenal catecholamine storing cells and on the heart was investigated in rats. The tissue catecholamine fluorescence intensity was determined by microfluorimetric quantitation of catecholamines. The maximal and final body weights were significantly lower in trained animals. The trained rats showed prominent increase of heart weight relative to body weight, while the adrenals did not enlarge. The adrenergic nerve fiber density of the heart and the fluorescence intensity of the terminal axons were significantly increased. There were no changes in the fluorescence intensity of the perikarya of the sympathetic neurons and the amount of extra-adrenal catecholamine storing cells after physical exercise. The volume of the superior cervical ganglion was doubled and the neuronal perikarya were enlarged in trained animals. The prolonged physical training throughout the life span of the rat gave new information about the reactions of the sympathetic nervous system to physical exercise.
研究了大鼠每日进行24个月体育训练对交感神经元、肾上腺、肾上腺外儿茶酚胺储存细胞及心脏的影响。通过对儿茶酚胺进行微荧光定量测定组织儿茶酚胺荧光强度。训练动物的最大体重和最终体重显著较低。训练大鼠的心脏重量相对于体重显著增加，而肾上腺未增大。心脏的肾上腺素能神经纤维密度和终末轴突的荧光强度显著增加。体育锻炼后交感神经元胞体的荧光强度和肾上腺外儿茶酚胺储存细胞数量无变化。训练动物的颈上神经节体积增加一倍，神经元胞体增大。在大鼠整个生命周期内进行的长期体育训练提供了有关交感神经系统对体育锻炼反应的新信息。
