Read G F, Wilson D W, Hughes I A, Griffiths K
J Endocrinol. 1984 Aug;102(2):265-8. doi: 10.1677/joe.0.1020265.
Menstrual cycle profiles of salivary progesterone were derived from daily samples obtained from 75 postmenarcheal girls aged between 12 and 17 years. Data were analysed to establish the proportion of girls exhibiting ovulatory cycles in each of several age groups following menarche or in groups based solely on chronological age. 'Luteal'-phase profiles of salivary progesterone, which were similar in shape to those characteristic of mature premenopausal women, were taken to indicate the probable occurrence of ovulation. The percentage of cycles in those subjects judged to be ovulatory, grouped according to gynaecological age, rose from 14% in the first year to 56% in the fourth year. Those classified according to chronological age, and where sufficient data permitted reliable estimates of the percentage of subjects ovulating, rose from 11% at 12 years of age to 64% for girls aged 16. These data are in reasonable concordance with published data using plasma progesterone and urinary methods for establishing ovulatory incidence, and indicate the value of salivary progesterone measurements in studies of ovarian function in adolescence.
唾液孕酮的月经周期曲线来自于75名初潮后年龄在12至17岁之间的女孩的每日样本。对数据进行分析，以确定在初潮后的几个年龄组中或仅按实际年龄分组的女孩中出现排卵周期的比例。唾液孕酮的“黄体期”曲线，其形状与成熟绝经前妇女的特征曲线相似，被认为表明可能发生了排卵。根据妇科年龄分组，被判定为排卵的受试者的周期百分比从第一年的14%上升到第四年的56%。根据实际年龄分类且有足够数据允许可靠估计排卵受试者百分比的情况，12岁女孩为11%，16岁女孩为64%。这些数据与使用血浆孕酮和尿液方法确定排卵发生率的已发表数据合理一致，并表明唾液孕酮测量在青春期卵巢功能研究中的价值。
