Guy R J, Dawson J L, Garrett J R, Laws J W, Thomas P K, Sharma A K, Watkins P J
J Neurol Neurosurg Psychiatry. 1984 Jul;47(7):686-91. doi: 10.1136/jnnp.47.7.686.
Two cases with intractable vomiting due to gastroparesis, a rare feature of diabetic autonomic neuropathy, are described. Both required surgical treatment. In the first a gastroenterostomy was complicated by reflux gastritis requiring a revision operation; in the second a gastrojejunostomy was successful. Electron microscopic studies of the vagus nerve in one of the cases showed a severe reduction in the density of unmyelinated axons, the surviving axons tending to be of small calibre. The severity of the abnormalities supports the view that diabetic gastroparesis is related to vagal denervation.
本文描述了两例因胃轻瘫导致顽固性呕吐的病例，胃轻瘫是糖尿病自主神经病变的一种罕见表现。两例均需手术治疗。第一例胃空肠吻合术后并发反流性胃炎，需再次手术；第二例胃空肠吻合术成功。其中一例的迷走神经电镜研究显示无髓鞘轴突密度严重降低，存活的轴突往往口径较小。这些异常的严重程度支持了糖尿病性胃轻瘫与迷走神经去神经支配有关的观点。
