• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脑脊液次黄嘌呤和黄嘌呤浓度作为脑积水儿童颅内压升高所致代谢损伤的指标

Cerebrospinal fluid hypoxanthine and xanthine concentrations as indicators of metabolic damage due to raised intracranial pressure in hydrocephalic children.

作者信息

Levin S D, Brown J K, Harkness R A

出版信息

J Neurol Neurosurg Psychiatry. 1984 Jul;47(7):730-3. doi: 10.1136/jnnp.47.7.730.

DOI:10.1136/jnnp.47.7.730
PMID:6747648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1027903/
Abstract

Intracranial pressure and cerebrospinal fluid hypoxanthine and xanthine concentrations were measured in hydrocephalic children with suspected raised intracranial pressure. There was a highly significant correlation between intracranial pressure and cerebrospinal fluid hypoxanthine and xanthine levels.

摘要

对疑似颅内压升高的脑积水患儿测量了颅内压以及脑脊液中次黄嘌呤和黄嘌呤的浓度。颅内压与脑脊液中次黄嘌呤和黄嘌呤水平之间存在高度显著的相关性。

相似文献

1
Cerebrospinal fluid hypoxanthine and xanthine concentrations as indicators of metabolic damage due to raised intracranial pressure in hydrocephalic children.脑脊液次黄嘌呤和黄嘌呤浓度作为脑积水儿童颅内压升高所致代谢损伤的指标
J Neurol Neurosurg Psychiatry. 1984 Jul;47(7):730-3. doi: 10.1136/jnnp.47.7.730.
2
Indicators of hypoxia in cerebrospinal fluid of hydrocephalic children with suspected shunt malfunction.疑似分流功能障碍的脑积水患儿脑脊液中的缺氧指标
Childs Nerv Syst. 1993 Aug;9(5):275-7. doi: 10.1007/BF00306272.
3
The concentrations of xanthine and hypoxanthine in cerebrospinal fluid as therapeutic guides in hydrocephalus.脑脊液中黄嘌呤和次黄嘌呤的浓度作为脑积水治疗的指导指标。
Childs Nerv Syst. 1986;2(3):109-11. doi: 10.1007/BF00270835.
4
Increased concentration of hypoxanthine in human central cerebrospinal fluid after subarachnoid haemorrhage.蛛网膜下腔出血后人体中枢脑脊液中次黄嘌呤浓度升高。
Acta Neurochir (Wien). 1985;77(1-2):52-9. doi: 10.1007/BF01402306.
5
Therapeutic criteria in hydrocephalic children.脑积水患儿的治疗标准。
Childs Nerv Syst. 1989 Dec;5(6):361-3. doi: 10.1007/BF00271893.
6
Alterations in cerebrospinal fluid uridine, hypoxanthine, and xanthine in head-injured patients.头部受伤患者脑脊液中尿苷、次黄嘌呤和黄嘌呤的变化。
Cell Mol Neurobiol. 1988 Jun;8(2):235-43. doi: 10.1007/BF00711249.
7
Cerebrospinal fluid nucleotide metabolites following non-convulsive status epilepticus.非惊厥性癫痫持续状态后的脑脊液核苷酸代谢产物
Dev Med Child Neurol. 1989 Apr;31(2):168-73. doi: 10.1111/j.1469-8749.1989.tb03975.x.
8
Concentration of purine compounds in the cerebrospinal fluid of infants suffering from sepsis, convulsions and hydrocephalus.患有败血症、惊厥和脑积水的婴儿脑脊液中嘌呤化合物的浓度。
J Perinat Med. 1995;23(3):167-74. doi: 10.1515/jpme.1995.23.3.167.
9
Cerebrospinal fluid nucleotide metabolites following short febrile convulsions.短暂热性惊厥后的脑脊液核苷酸代谢产物
Dev Med Child Neurol. 1989 Apr;31(2):161-7. doi: 10.1111/j.1469-8749.1989.tb03974.x.
10
HPLC method for measurement of purine nucleotide degradation products in cerebrospinal fluid.用于测量脑脊液中嘌呤核苷酸降解产物的高效液相色谱法。
Clin Chem. 1996 May;42(5):756-60.

引用本文的文献

1
Hypoxanthine is a metabolic biomarker for inducing GSDME-dependent pyroptosis of endothelial cells during ischemic stroke.次黄嘌呤是一种代谢生物标志物,可在缺血性中风期间诱导内皮细胞中依赖 GSDME 的细胞焦亡。
Theranostics. 2024 Sep 16;14(15):6071-6087. doi: 10.7150/thno.100090. eCollection 2024.
2
Cerebrospinal fluid purine metabolites after complex febrile convulsions.复杂性热性惊厥后的脑脊液嘌呤代谢产物
Childs Nerv Syst. 1996 Jun;12(6):315-7. doi: 10.1007/BF00301019.
3
Value of transcranial Doppler indices in predicting raised ICP in infantile hydrocephalus. A study with review of the literature.

本文引用的文献

1
Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow.缺氧时的心脏核苷酸:在冠状动脉血流调节中的可能作用。
Am J Physiol. 1963 Feb;204:317-22. doi: 10.1152/ajplegacy.1963.204.2.317.
2
High-performance liquid chromatographic methods for base and nucleoside analysis in extracellular fluids and in cells.用于细胞外液和细胞中碱基与核苷分析的高效液相色谱法。
J Chromatogr. 1981 Dec 11;226(2):369-81. doi: 10.1016/s0378-4347(00)86071-5.
3
Complications in the treatment of hydrocephalus in children. A comparison of ventriculoatrial and ventriculoperitoneal shunts in a 20-year material.
经颅多普勒指数在预测婴儿脑积水颅内压升高方面的价值。一项文献综述研究。
Childs Nerv Syst. 1995 Oct;11(10):595-603. doi: 10.1007/BF00300999.
4
Introduction to the age-related diagnosis (ARD) index: an age at presentation related index for diagnostic use.年龄相关诊断(ARD)指数简介:一种用于诊断的就诊年龄相关指数。
J Inherit Metab Dis. 1993;16(2):161-70. doi: 10.1007/BF00710248.
5
Indicators of hypoxia in cerebrospinal fluid of hydrocephalic children with suspected shunt malfunction.疑似分流功能障碍的脑积水患儿脑脊液中的缺氧指标
Childs Nerv Syst. 1993 Aug;9(5):275-7. doi: 10.1007/BF00306272.
6
The concentrations of xanthine and hypoxanthine in cerebrospinal fluid as therapeutic guides in hydrocephalus.脑脊液中黄嘌呤和次黄嘌呤的浓度作为脑积水治疗的指导指标。
Childs Nerv Syst. 1986;2(3):109-11. doi: 10.1007/BF00270835.
7
Alterations in cerebrospinal fluid uridine, hypoxanthine, and xanthine in head-injured patients.头部受伤患者脑脊液中尿苷、次黄嘌呤和黄嘌呤的变化。
Cell Mol Neurobiol. 1988 Jun;8(2):235-43. doi: 10.1007/BF00711249.
8
Clinical biochemistry of the neonatal period: immaturity, hypoxia, and metabolic disease.新生儿期临床生物化学:不成熟、缺氧与代谢性疾病。
J Clin Pathol. 1987 Sep;40(9):1128-44. doi: 10.1136/jcp.40.9.1128.
9
Therapeutic criteria in hydrocephalic children.脑积水患儿的治疗标准。
Childs Nerv Syst. 1989 Dec;5(6):361-3. doi: 10.1007/BF00271893.
10
Clinical and biochemical assessments of damage due to perinatal asphyxia: a double blind trial of a quantitative method.围产期窒息所致损伤的临床与生化评估:一种定量方法的双盲试验
J Clin Pathol. 1988 Mar;41(3):247-52. doi: 10.1136/jcp.41.3.247.
儿童脑积水治疗中的并发症。对20年资料中的脑室心房分流术和脑室腹腔分流术的比较。
Acta Paediatr Scand. 1983 May;72(3):385-90. doi: 10.1111/j.1651-2227.1983.tb09733.x.
4
Ratio of the concentration of hypoxanthine to creatinine in urine from newborn infants: a possible indicator for the metabolic damage due to hypoxia.新生儿尿液中次黄嘌呤与肌酐的浓度比值:缺氧所致代谢损伤的一个可能指标。
Br J Obstet Gynaecol. 1983 May;90(5):447-52. doi: 10.1111/j.1471-0528.1983.tb08942.x.
5
Quantitative measurements of the urinary excretion of creatinine, uric acid, hypoxanthine and xanthine, uracil, cyclic AMP, and cyclic GMP in healthy newborn infants.健康新生儿尿中肌酐、尿酸、次黄嘌呤、黄嘌呤、尿嘧啶、环磷酸腺苷和环磷酸鸟苷排泄量的定量测定。
Eur J Pediatr. 1980 Mar;133(2):157-61. doi: 10.1007/BF00441585.
6
[Decomposition of free nucleotides in the rat heart, skeletal muscle, brain and liver in oxygen deficiency].[缺氧状态下大鼠心脏、骨骼肌、脑及肝脏中游离核苷酸的分解]
Pflugers Arch Gesamte Physiol Menschen Tiere. 1966;292(3):239-54.
7
Metabolic alterations in brain during anoxic-anoxia and subsequent recovery.缺氧-缺血期间及随后恢复过程中大脑的代谢改变。
Arch Neurol. 1973 Dec;29(6):385-90. doi: 10.1001/archneur.1973.00490300047005.
8
The determination of hypoxanthine and xanthine with a PO2 electrode.用氧分压电极测定次黄嘌呤和黄嘌呤。
Pediatr Res. 1975 Jul;9(7):575-9. doi: 10.1203/00006450-197507000-00004.
9
Alteration of the hypoxanthine level in cerebrospinal fluid as an indicator of tissue hypoxia.脑脊液中次黄嘌呤水平的改变作为组织缺氧的一个指标。
Brain Res. 1976 Aug 6;112(1):188-9. doi: 10.1016/0006-8993(76)90349-8.
10
Hypoxanthine as an indicator of tissue hypoxia. A study of plasma, cerebro-spinal and brain tissue concentrations.次黄嘌呤作为组织缺氧的指标。血浆、脑脊液及脑组织浓度的研究。
J Oslo City Hosp. 1977 Mar;27(3):29-40.