Pepys M B, Dash A C
Lancet. 1977 May 14;1(8020):1029-31. doi: 10.1016/s0140-6736(77)91260-0.
The P component of amyloid (protein AP, pentagonal unit) has been isolated from normal serum by using its hitherto undescribed calcium-dependent affinity for agarose. The presence of P component in all forms of amyloid may be due to this calcium-dependent binding to certain polyanions.
淀粉样蛋白的P成分(蛋白质AP,五边形单位)已通过利用其迄今未被描述的对琼脂糖的钙依赖性亲和力从正常血清中分离出来。所有形式的淀粉样蛋白中都存在P成分,这可能归因于其与某些聚阴离子的这种钙依赖性结合。