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[移植排斥反应危象期间异位心脏移植的电活动和冠状动脉血流变化]

[Changes in the electrical activity and coronary blood flow of a heterotopic heart allograft during a graft rejection crisis].

作者信息

Dvortsin G F, Karpel' E G, Portnoĭ V F

出版信息

Kardiologiia. 1982;22(6):54-8.

PMID:6750204
Abstract

In 12 experiments on dogs heterotopic cardiac allotransplantation on the recipient's neck has been performed. During the transplant survival its electrical activity and the coronary blood flow (CBF) were recorded with an implanted sensor of electromagnetic flowmeter. The combination of relatively low CBF and the amplitude of R wave during the first hours after transplantation with a high heart rate is a poor prognostic sign. Oscillations of CBF run parallel to changes of ECG when the viability of the transplant is retained, during the rejection crisis these changes do not correlate. The significance of comprehensive assessment of the cardiac function with the use of ECG and CBF measurement and comparison of their absolute figures and dynamics is shown to be of importance for the early diagnosis of the rejection crisis.

摘要

在12只狗身上进行了受体颈部异位心脏同种异体移植实验。在移植存活期间,用植入的电磁流量计传感器记录其电活动和冠状动脉血流量(CBF)。移植后最初几小时内,相对较低的CBF和R波振幅与较高的心率相结合是预后不良的迹象。当移植的活力得以保留时,CBF的振荡与心电图的变化平行,在排斥反应期,这些变化不相关。结果表明,利用心电图和CBF测量综合评估心脏功能,并比较其绝对值和动态变化,对于排斥反应期的早期诊断具有重要意义。

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1
[Changes in the electrical activity and coronary blood flow of a heterotopic heart allograft during a graft rejection crisis].[移植排斥反应危象期间异位心脏移植的电活动和冠状动脉血流变化]
Kardiologiia. 1982;22(6):54-8.
2
Coronary blood flow does not decrease during allograft rejection in heterotopic heart transplants.在异位心脏移植中,同种异体移植排斥反应期间冠状动脉血流量不会减少。
J Heart Lung Transplant. 1991 Mar-Apr;10(2):251; 6; discussion 256-7.
3
Changes in coronary blood flow during rejection of the orthotopically transplanted canine heart.同种异体原位移植犬心脏排斥反应期间冠状动脉血流的变化。
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4
European Association of Cardiovascular Imaging/Cardiovascular Imaging Department of the Brazilian Society of Cardiology recommendations for the use of cardiac imaging to assess and follow patients after heart transplantation.欧洲心血管影像协会/巴西心脏病学会心血管影像学部关于心脏移植后评估和随访患者使用心脏影像的建议。
Eur Heart J Cardiovasc Imaging. 2015 Sep;16(9):919-48. doi: 10.1093/ehjci/jev139. Epub 2015 Jul 2.
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6
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7
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8
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Platelets in hyperacute rejection of heterotopic cardiac allografts in presensitized dogs. An experimental study.预致敏犬异位心脏同种异体移植超急性排斥反应中的血小板。一项实验研究。
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