Suppr超能文献

Inhibitory action of gossypol on enzymes and growth of Trypanosoma cruzi.

作者信息

Montamat E E, Burgos C, Gerez de Burgos N M, Rovai L E, Blanco A, Segura E L

出版信息

Science. 1982 Oct 15;218(4569):288-9. doi: 10.1126/science.6750791.

Abstract

Gossypol, a phenolic compound isolated from the cotton plant, is a powerful inhibitor of nicotinamide adenine dinucleotide-linked enzymes (alpha-hydroxyacid dehydrogenase and malate dehydrogenase) of Trypanosoma cruzi, the parasite that causes Chagas' disease. Parasites at the epimastigote stage that were incubated for 5 minutes with 100 micromolar gossypol were completely immobilized. Concentrations of gossypol as low as 0.01 micromolar markedly reduced the growth rate of T. cruzi in culture.

摘要

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验