Knudsen L, Marcussen H, Fleckenstein P, Pedersen E B, Jarnum S
Scand J Gastroenterol. 1978;13(4):433-6. doi: 10.3109/00365527809181917.
In a selected material of 228 patients with chronic inflammatory bowel disease (CIBD) the incidence of urolithiasis was 15% (95% confidence limit 11-21). The tendency to urolithiasis is significantly correlated to small-bowel resection and its extent and to obstruction in the urinary tract. On the other hand, there is no definite correlation to the duration or extent of the bowel disease. The significant correlation between urolithiasis and ileal resection is in agreement with the hyperabsorption of oxalate as an important cause of stone formation demonstrated by others. That local factors too play an essential role in the formation of urinary calculi is apparent from the increased incidence of urolithiasis in obstruction of the urinary tract. The incidence of urolithiasis was particularly high (22-25%) among patients with ileostomies. The few and negligible symptoms of and sequelae to, urolithiasis in CIBD encourage a conservative attitude.
在选取的228例慢性炎症性肠病（CIBD）患者中，尿路结石的发病率为15%（95%置信区间为11%-21%）。尿路结石的发病倾向与小肠切除术及其范围以及尿路梗阻显著相关。另一方面，与肠道疾病的病程或范围没有明确的相关性。尿路结石与回肠切除术之间的显著相关性与其他人所证实的草酸盐过度吸收作为结石形成的重要原因相一致。从尿路梗阻时尿路结石发病率的增加可以明显看出，局部因素在尿路结石的形成中也起着至关重要的作用。回肠造口术患者的尿路结石发病率特别高（22%-25%）。CIBD患者尿路结石的症状和后遗症较少且可忽略不计，这鼓励采取保守态度。
