Singer H A, Nelson M M, Beighton P H
S Afr Med J. 1978 Apr 22;53(16):626-7.
In the first phase of a programme for the prevention of neural tube defects at a population level, information has been obtained concerning 285 infants born with open neural tube defects. As in other parts of the world, the months of conception of affected infants clustered in the second quarter of the year and the majority of the parents were members of lower income groups. In the years 1975-1977, the incidence of anencephaly and spina bifida in White South African patients was similar to that generally encountered in Western Europe. However, in the non-White populations the separate and combined incidence were significantly lower. It is emphasized that these are preliminary figures and that they might be subject to ascertainment biases.
在一项针对神经管缺陷进行人群层面预防的项目的第一阶段，已获取了有关285例患有开放性神经管缺陷婴儿的信息。与世界其他地区一样，受影响婴儿的受孕月份集中在一年中的第二季度，且大多数父母属于低收入群体。在1975年至1977年期间，南非白人患者无脑儿和脊柱裂的发病率与西欧普遍出现的发病率相似。然而，在非白人人群中，单独及合并发病率显著较低。需要强调的是，这些是初步数据，可能存在确诊偏倚。
