Beitz A J
Neurosci Lett. 1982 Oct 23;32(3):223-8. doi: 10.1016/0304-3940(82)90297-x.
The origins of the serotonergic projections to the spinal trigeminal nucleus in the rat were determined utilizing the combined HRP retrograde transport-immunohistochemical technique. The areas providing the greatest number of serotonergic afferent projections to the spinal trigeminal nucleus are the raphe magnus, raphe obscurus, nucleus reticularis gigantocellularis pars alpha, and the nucleus reticularis paragigantocellularis. A smaller serotonergic input to the spinal trigeminal nucleus was found to arise from the raphe pallidus, periaqueductal gray, raphe dorsalis, raphe pontis and mesencephalic reticular formation. These results indicate that the spinal trigeminal nucleus receives serotonergic input from all levels of the brainstem including the midbrain cell group B7.
利用辣根过氧化物酶（HRP）逆行运输-免疫组织化学联合技术，确定了大鼠中5-羟色胺能投射至三叉神经脊束核的起源。向三叉神经脊束核提供最多5-羟色胺能传入投射的区域是中缝大核、中缝隐核、巨细胞网状核α部和旁巨细胞网状核。发现向三叉神经脊束核的5-羟色胺能输入较少的区域有中缝苍白核、导水管周围灰质、中缝背核、中缝脑桥核和中脑网状结构。这些结果表明，三叉神经脊束核接受来自脑干所有水平（包括中脑细胞群B7）的5-羟色胺能输入。
