Pritchard K A, Karpen C W, Merola A J, Panganamala R V
Prostaglandins Leukot Med. 1982 Oct;9(4):373-8. doi: 10.1016/0262-1746(82)90093-2.
Rabbits were maintained on vitamin E-deficient and vitamin E-supplemented diets. Thrombin- and collagen-induced thromboxane A2 production were significantly elevated in vitamin E-deficient platelets. Conversion of arachidonic acid to platelet thromboxane A2 was unchanged between the two groups of animals. Prostacyclin I2 production in the aortas from vitamin E-deficient rabbits was significantly elevated.
兔子分别饲喂维生素E缺乏和补充维生素E的日粮。维生素E缺乏的血小板中,凝血酶和胶原诱导的血栓素A2生成显著升高。两组动物之间,花生四烯酸向血小板血栓素A2的转化没有变化。维生素E缺乏的兔子主动脉中前列环素I2的生成显著升高。