Ellis N, Gallant J
Mol Gen Genet. 1982;188(2):169-72. doi: 10.1007/BF00332670.
Electrophoretic heterogeneity in a set of selected proteins is used to estimate the average error frequency during translation. Estimates based upon streptomycin-induced heterogeneity as well as mistranslation of an ochre codon yield an average error frequency of 4 x 10(-4) for normally growing cells.
一组选定蛋白质中的电泳异质性被用于估计翻译过程中的平均错误频率。基于链霉素诱导的异质性以及赭石密码子错义翻译的估计得出,正常生长细胞的平均错误频率为4×10⁻⁴。