Yamamoto T, Tamura T, Yokota T, Takano T
Mol Gen Genet. 1982;188(2):356-9. doi: 10.1007/BF00332701.
We have determined the nucleotide sequence at the distal end of the heat-labile enterotoxin subunit A (LT-A) gene (toxA) originating from human enterotoxigenic Escherichia coli. The sequenced region covers the entire LT-A2 region and a part of the LT-A1 region. In confirming our previous prediction based on product analysis of clones toxA regions, the data suggest the overlapping of the distal end (5'-TTA TGA) of toxA with the proximal end (5'-ATG AAT) of the LT subunit B gene (toxB), in the sequences 5'-TTATGAAT. Some additional characteristics of the LT operon as well as of the products are discussed.
我们已经确定了源自人产肠毒素大肠杆菌的热不稳定肠毒素亚基A（LT-A）基因（toxA）远端的核苷酸序列。测序区域涵盖了整个LT-A2区域和部分LT-A1区域。在根据克隆的toxA区域的产物分析证实我们之前的预测时，数据表明在5'-TTATGAAT序列中，toxA的远端（5'-TTA TGA）与LT亚基B基因（toxB）的近端（5'-ATG AAT）重叠。文中还讨论了LT操纵子以及产物的一些其他特征。
