Fraisse J, Frocrain-Herchkovitch C, Turc-Carel C
Pathol Biol (Paris). 1982 Nov;30(9):766-8.
Chromosome banding techniques have been useful to define abnormal chromosomes in acute leukemia. The comparison between cases reported from different centers has been possible only with the acceptance of a universal system of classification and nomenclature for acute leukemia as well as for chromosomal rearrangements. Chromosomes abnormalities in acute leukemia are found in about 50 per cent of patients. They appear to be non random. Clinical, morphologic and cytogenetic findings have been correlated. Diagnosis and prognosis significance of chromosome abnormalities is of importance. The problem of normal or so called normal cells in 50 per cent of acute leukemia is set.
染色体显带技术对于确定急性白血病中的异常染色体很有用。只有接受急性白血病以及染色体重排的通用分类和命名系统，不同中心报告的病例之间才有可能进行比较。约50%的急性白血病患者存在染色体异常。这些异常似乎并非随机出现。临床、形态学和细胞遗传学发现已相互关联。染色体异常的诊断和预后意义很重要。50%的急性白血病中存在正常或所谓正常细胞的问题由此产生。
