奈替米星的均相酶免疫测定法。
Homogeneous enzyme immunoassay for netilmicin.
作者信息
Wenk M, Hemmann R, Follath F
出版信息
Antimicrob Agents Chemother. 1982 Dec;22(6):954-7. doi: 10.1128/AAC.22.6.954.
Abstract
A newly developed homogeneous enzyme immunoassay for the determination of netilmicin in serum was evaluated and compared with a radioenzymatic assay. A total of 102 serum samples from patients treated with netilmicin were measured by both methods. This comparison showed an excellent correlation (r = 0.993). The enzyme immunoassay has proved to be precise, accurate, and specific. Because of its rapidity and the ease of performance, this method is a useful alternative to current assays for monitoring serum netilmicin concentrations.
摘要
评估了一种新开发的用于测定血清中奈替米星的均相酶免疫分析法，并与放射酶分析法进行了比较。用这两种方法对总共102份接受奈替米星治疗的患者的血清样本进行了检测。这种比较显示出极好的相关性（r = 0.993）。酶免疫分析法已被证明是精确、准确且特异的。由于其快速性和操作简便性，该方法是目前监测血清奈替米星浓度的检测方法的一种有用替代方法。
相似文献
1
Homogeneous enzyme immunoassay for netilmicin.奈替米星的均相酶免疫测定法。
Antimicrob Agents Chemother. 1982 Dec;22(6):954-7. doi: 10.1128/AAC.22.6.954.
2
Assay of netilmicin, using enzyme immunoassay for gentamicin.使用庆大霉素酶免疫测定法测定奈替米星。
Antimicrob Agents Chemother. 1982 Mar;21(3):399-401. doi: 10.1128/AAC.21.3.399.
3
Evaluation of five immunological methods for the assay of serum netilmicin.五种血清奈替米星检测免疫方法的评估
Pharm Weekbl Sci. 1984 Apr 27;6(2):68-74. doi: 10.1007/BF01953957.
4
Assay of netilmicin in serum by substrate labelled fluoroimmunoassay.用底物标记荧光免疫分析法测定血清中的奈替米星。
J Antimicrob Chemother. 1983 Oct;12(4):403-6. doi: 10.1093/jac/12.4.403.
5
Serum assays of netilmicin by enzyme multiplied immunoassay technique and bioassay: a comparative study.采用酶放大免疫分析技术和生物测定法对奈替米星进行血清检测：一项对比研究。
Antimicrob Agents Chemother. 1982 Dec;22(6):1058-60. doi: 10.1128/AAC.22.6.1058.
6
Fluorescence polarization immunoassay of gentamicin or netilmicin in blood spotted on filter paper.滤纸上血样中庆大霉素或奈替米星的荧光偏振免疫测定法。
Clin Chem. 1989 May;35(5):867-9.
7
Assay of netilmicin in serum with the gentamicin radioimmunoassay kit.
Am J Hosp Pharm. 1982 May;39(5):784, 787-8.
8
Rapid bioluminescent assay for determining netilmicin and tobramycin concentrations in serum.
Eur J Clin Microbiol. 1983 Dec;2(6):564-7. doi: 10.1007/BF02016566.
9
Performance characteristics of bioassay, radioenzymatic assay, homogeneous enzyme immunoassay, and high-performance liquid chromatographic determination of serum gentamicin.生物测定、放射酶测定、均相酶免疫测定以及血清庆大霉素的高效液相色谱测定的性能特征
Antimicrob Agents Chemother. 1982 Jan;21(1):19-25. doi: 10.1128/AAC.21.1.19.
10
Serum gentamicin, netilmicin and tobramycin assays by high performance liquid chromatography.采用高效液相色谱法测定血清庆大霉素、奈替米星和妥布霉素含量。
J Antimicrob Chemother. 1982 Oct;10(4):311-8. doi: 10.1093/jac/10.4.311.
引用本文的文献
1
FMT intervention decreases urine 5-HIAA levels: a randomized double-blind controlled study.粪菌移植干预可降低尿中5-羟吲哚乙酸水平：一项随机双盲对照研究。
Front Med (Lausanne). 2024 Oct 18;11:1411089. doi: 10.3389/fmed.2024.1411089. eCollection 2024.
2
Serum level monitoring of antibacterial drugs. A review.抗菌药物的血清水平监测。综述。
Clin Pharmacokinet. 1984 Nov-Dec;9(6):475-92. doi: 10.2165/00003088-198409060-00001.
3
Effect of cardiopulmonary bypass on vancomycin and netilmicin disposition.体外循环对万古霉素和奈替米星处置的影响。
Antimicrob Agents Chemother. 1988 May;32(5):631-5. doi: 10.1128/AAC.32.5.631.
4
Netilmicin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.奈替米星。对其抗菌活性、药代动力学特性及治疗用途的综述。
Drugs. 1989 Nov;38(5):703-56. doi: 10.2165/00003495-198938050-00003.
本文引用的文献
1
Plasma concentration monitoring of aminoglycosides.
J Antimicrob Chemother. 1981 Jul;8 Suppl A:37-43. doi: 10.1093/jac/8.suppl_a.37.
2
Concepts for aminoglycoside serum level monitoring.氨基糖苷类药物血清水平监测的概念。
J Antimicrob Chemother. 1982 Mar;9(3):168-9. doi: 10.1093/jac/9.3.168.
3
Improving the sensitivity of gentamicin enzyme immunoassay.提高庆大霉素酶免疫测定的灵敏度。
Clin Chem. 1982 Jan;28(1):248.
4
Rapid, reproducible enzyme immunoassay for tobramycin.用于妥布霉素的快速、可重复的酶免疫测定法。
J Clin Microbiol. 1981 Jan;13(1):93-6. doi: 10.1128/jcm.13.1.93-96.1981.
5
Evaluation of an enzyme immunoassay for serum gentamicin.血清庆大霉素酶免疫测定法的评估
Antimicrob Agents Chemother. 1980 May;17(5):776-8. doi: 10.1128/AAC.17.5.776.
6
Comparative nephrotoxicities of netilmicin and gentamicin in rats.奈替米星和庆大霉素对大鼠的肾毒性比较
Antimicrob Agents Chemother. 1976 Nov;10(5):845-9. doi: 10.1128/AAC.10.5.845.
7
In vitro studies on netilmicin, a new aminoglycoside antibiotic.关于新氨基糖苷类抗生素奈替米星的体外研究。
Antimicrob Agents Chemother. 1977 Jun;11(6):1017-20. doi: 10.1128/AAC.11.6.1017.
8
The acetyltransferase enzyme method for the assay of serum gentamicon concentrations and a comparison with other methods.用于测定血清庆大霉素浓度的乙酰转移酶酶法及与其他方法的比较。
J Clin Pathol. 1975 Feb;28(2):140-5. doi: 10.1136/jcp.28.2.140.
9
Comparative ototoxic liability of netilmicin and gentamicin.奈替米星与庆大霉素的比较耳毒性责任
Arch Otolaryngol. 1978 Oct;104(10):579-84. doi: 10.1001/archotol.1978.00790100033007.
10
Multicompartment pharmacokinetics of netilmicin.奈替米星的多房室药代动力学
Eur J Clin Pharmacol. 1979 Nov;16(5):331-4. doi: 10.1007/BF00605631.
Zotero 插件