Neumann H A, Berretty P J, Faber W R
Ann Dermatol Venereol. 1982;109(8):649-53.
This paper reports an immunofluorescence (IF) study of the skin of 16 patients with chronic discoid localised lupus erythematosus and 5 patients with cutaneous disseminated lupus erythematosus. In the majority of the cases (18), we have found immunoglobulin and complement deposits not only along the dermoepidermal junction, but also in the blood vessel walls. In these deposits there was a predominance of IgM. It appears that an immune complex vasculitis in the skin can be found in patients from the entire lupus erythematosus spectrum. The discovery of immunoglobulins and complement deposits in the blood vessel walls of the involved skin of patients with discoid lupus erythematosus, suggests that it can be considered as an important (and even characteristic) feature of the disease.
本文报道了对16例慢性盘状局限性红斑狼疮患者和5例皮肤播散性红斑狼疮患者皮肤的免疫荧光（IF）研究。在大多数病例（18例）中，我们不仅在真皮表皮交界处，而且在血管壁中发现了免疫球蛋白和补体沉积。在这些沉积物中，IgM占主导地位。看来，在整个红斑狼疮谱系的患者中都可以发现皮肤免疫复合物血管炎。在盘状红斑狼疮患者受累皮肤的血管壁中发现免疫球蛋白和补体沉积，表明这可被视为该疾病的一个重要（甚至是特征性）特征。
