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[从不同菌株实验动物中获得的葡萄球菌过敏原的生物活性特征]

[Characteristics of the biological activity of staphylococcal allergens obtained from various strains laboratory animals].

作者信息

Runova V F, Poliakova T M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Jun(6):92-5.

PMID:676602
Abstract

The authors suggest an optimal scheme of guinea pig sensitization for the assessment of specific activity of staphylococcal allergens. On milliard cells of killed staphylococcal culture are injected to the animals into the paws of the limbs; two and a half weeks later an intradermal test with an allergen in a dose of 10 microgram by protein was made. Differences in the specific activity of staphylococcal allergens prepared of various strains were revealed. Biochemical properties of the strains proved to be of significance for the sensitization.

摘要

作者提出了一种用于评估葡萄球菌过敏原比活性的豚鼠致敏优化方案。将十亿个经杀死的葡萄球菌培养细胞注射到动物四肢的爪子中;两周半后,进行皮内试验,注射剂量为10微克蛋白质的过敏原。揭示了由不同菌株制备的葡萄球菌过敏原比活性的差异。结果证明菌株的生化特性对致敏具有重要意义。

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