Upadhyay M P, West E P, Sharma A P
Br J Ophthalmol. 1980 Jan;64(1):30-2. doi: 10.1136/bjo.64.1.30.
A case of Aspergillus flavus keratitis treated successfully with 4% suspension of thiabendazole is reported. This seems to be the first case of successful treatment of keratomycosis with thiabendazole. All other reported cases treated with this drug either had their eyes removed or did not retain any useful vision. Its ability to penetrate ocular tissues, ability to remain in concentrations higher than the minimal inhibitory concentration of many fungi, and broad spectrum of activity make it a worthwhile drug for further investigation in keratomycosis.
报告了1例用4%噻苯达唑混悬液成功治疗的黄曲霉角膜炎病例。这似乎是首例用噻苯达唑成功治疗角膜真菌病的病例。其他所有用该药治疗的报告病例要么眼球被摘除，要么未保留任何有用视力。其穿透眼组织的能力、保持高于许多真菌最低抑菌浓度的浓度的能力以及广谱活性，使其成为一种值得在角膜真菌病中进一步研究的药物。
