Kobrine A I, Evans D E, Rizzoli H V
J Neurol Sci. 1980 Feb;45(1):65-72. doi: 10.1016/s0022-510x(80)80007-4.
In this experiment CER and SER were monitored as blood flow was progressively lowered by lowering the systemic arterial pressure below the lower limits of autoregulation (bleeding). Blood flow in the brain and dorsal column of the spinal cord was monitored and recorded with the hydrogen clearance method. Long tract neural conduction in the spinal cord appeared quite refractory to the effects of ischemia and disappeared only after 8--18 min of essentially absolute ischemia. The CER was more sensitive to the effects of ischemia, disappearing first in one animal and returning later in all of the animals. The SER returned in all animals after re-infusion of the blood and re-establishment of the blood flow even after a 13--23 min period of absolute ischemia and a 5 min period of electrical silence.
在本实验中，通过将体动脉压降低至自动调节下限以下（放血）来逐渐降低血流，同时监测脑电反应（CER）和脊髓诱发电位（SER）。采用氢清除法监测并记录脑和脊髓背柱的血流。脊髓长束神经传导对缺血效应表现出相当的耐受性，仅在基本完全缺血8 - 18分钟后才消失。CER对缺血效应更敏感，在一只动物中首先消失，随后在所有动物中恢复。即使在经历13 - 23分钟的完全缺血和5分钟的电静息期后，在重新输血和恢复血流后，所有动物的SER均恢复。
