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黑腹果蝇幼虫唾液腺的分泌蛋白:一种蛋白质与一个胀泡的细胞遗传学相关性

The secretory proteins of the larval salivary gland of Drosophila melanogaster: Cytogenetic correlation of a protein and a puff.

作者信息

Velissariou V, Ashburner M

出版信息

Chromosoma. 1980;77(1):13-27. doi: 10.1007/BF00292038.

DOI:10.1007/BF00292038
PMID:6768531
Abstract

The gene for a major salivary gland secretion protein (Sgs-1) in Drosophila melanogaster has been mapped to chromosome 2 between dp (13.0) and cl (16.5). In the late third instar larva, a puff forms in this region. This puff (25 B) regresses as the ecdysteroid concentration increases prior to puparium formation. Quantitative analysis of the secretory protein 1, showed that, when present in extra dose, region 25 B results in a significant elevation in its relative amount. This suggests that the structural gene for this protein is localized in this region and that its synthesis is directly correlated to the activity of the 25 B puff.

摘要

黑腹果蝇中一种主要唾液腺分泌蛋白(Sgs-1)的基因已被定位到2号染色体上dp(13.0)和cl(16.5)之间的区域。在三龄幼虫后期,该区域会形成一个胀泡。在化蛹前随着蜕皮甾类浓度升高,这个胀泡(25B)会消退。对分泌蛋白1的定量分析表明,当额外增加剂量时,25B区域会使其相对含量显著升高。这表明该蛋白的结构基因位于这个区域,并且其合成与25B胀泡的活性直接相关。

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本文引用的文献

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[The puffs of salivary gland chromosomes of Drosophilia melanogaster. Part 1. Observations on the behavior of a typical puff in the normal strain and in two mutants, giant and lethal giant larvae].[黑腹果蝇唾液腺染色体的胀泡。第1部分。关于正常品系以及两种突变体(巨型和致死巨型幼虫)中典型胀泡行为的观察]
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