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全科医疗中脂质代谢紊乱的筛查与治疗控制(作者译)

[Screening and therapy control of lipid metabolism disturbances in general practice (author's transl)].

作者信息

Assmann G, Schriewer H

出版信息

MMW Munch Med Wochenschr. 1980 Mar 28;122(13):449-52.

PMID:6769013
Abstract

The determination of total cholesterol and triglycerides in fasting serum is the basic program for routine diagnosis and therapy control of lipid metabolic defects. With the introduction of routine determination of HDL-cholesterol and LDL-cholesterol into the laboratory of the general practitioner, differential diagnosis of lipid metabolism disorders and therefore an improved recognition of the coronary risk becomes possible. The combination of hypertriglyceridemia and a low HDL-cholesterol as a possible indicator of diminished intravascular lipolysis is especially significant for the recognition of individual risks. The indications for the diagnosis and therapeutic control of hyperlipidemia as well as the value of the lipid parameters for the prediction and early diagnosis of coronary heart disease is discussed.

摘要

空腹血清中总胆固醇和甘油三酯的测定是脂质代谢缺陷常规诊断和治疗控制的基本项目。随着全科医生实验室引入高密度脂蛋白胆固醇(HDL-胆固醇)和低密度脂蛋白胆固醇(LDL-胆固醇)的常规测定,脂质代谢紊乱的鉴别诊断以及对冠心病风险的更好识别成为可能。高甘油三酯血症和低HDL-胆固醇的组合作为血管内脂肪分解减少的可能指标,对于识别个体风险尤为重要。本文讨论了高脂血症诊断和治疗控制的指征以及脂质参数对冠心病预测和早期诊断的价值。

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