Dvorák M, Sevcík B, Liebichová L
Vet Med (Praha). 1980 Feb;25(2):81-9.
The preparation Chronicin solutio ad usum vet. (SPOFA) (a 15% solution of CHF-base in propylene glycol) is to be orally administered to poultry in drinking water. The recommended doses (5 ml per 1 of water in chickens and turkey-poults and 3 ml per 1 of water in ducklings) produce, in the blood serum, CHF concentrations which act bacteriostatically on sensitive microbial strains [chickens--mean 2.60 micrograms per ml (0.71--6.25), ducks--mean 2.11 micrograms per ml (0.87--4.72)]. After dilution, the preparation is stable in the drinkers at least 24 hours and does not reduce the intake of drinking water in short-term administration. CHF residues remained in the organs of hens six days after the five-day therapy and in the eggs of hens nine days after the therapy. It is recommended, therefore, to respect a nine-day protective period in tissues and a 12-day protective period in eggs (between the end of therapy and processing for consumption).
久效磷旧制剂溶液（SPOFA）（15%的CHF碱丙二醇溶液）通过饮水口服给予家禽。推荐剂量（鸡和小火鸡每1升水5毫升，小鸭每1升水3毫升）可在血清中产生对敏感微生物菌株具有抑菌作用的CHF浓度[鸡——平均每毫升2.60微克（0.71 - 6.25），鸭——平均每毫升2.11微克（0.87 - 4.72）]。稀释后，该制剂在饮水器中至少稳定24小时，短期给药不会减少饮水量。在为期五天的治疗后六天，母鸡的器官中仍有CHF残留，治疗后九天，母鸡的鸡蛋中仍有CHF残留。因此，建议在组织中遵守九天的保护期，在鸡蛋中遵守十二天的保护期（从治疗结束到加工供消费之间）。
