Brown D T, Morison D H, Covino B G, Scott D B
Br J Anaesth. 1980 Apr;52(4):419-22. doi: 10.1093/bja/52.4.419.
A double-blind comparison of carbonated bupivacaine and bupivacaine hydrochloride in extradural anaesthesia was performed in 40 patients. No significant differences in the onset times, sensory blockade, motor blockade and duration of anaesthesia were demonstrated. Carbonated bupivacaine does not appear to offer any advantage over the hydrochloride salt for extradural anaesthesia.
对40例患者进行了碳酸布比卡因和盐酸布比卡因在硬膜外麻醉中的双盲比较。结果显示，在起效时间、感觉阻滞、运动阻滞和麻醉持续时间方面没有显著差异。对于硬膜外麻醉，碳酸布比卡因似乎并不比盐酸盐具有任何优势。
