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碳酸利多卡因与盐酸利多卡因用于硬膜外麻醉的双盲比较

A double-blind comparison of carbonated lidocaine and lidocaine hydrochloride in epidural anaesthesia.

作者信息

Morison D H

出版信息

Can Anaesth Soc J. 1981 Jul;28(4):387-9. doi: 10.1007/BF03007808.

DOI:10.1007/BF03007808
PMID:7020890
Abstract

Twenty patients having a standard epidural anaesthetic were randomly assigned to receive 20 ml of either carbonated lidocaine 1.73 per cent or lidocaine hydrochloride 2.0 per cent, containing epinephrine 1:200,000. An observer unaware of the solution used measured speed of onset, quality of block, and duration of action. No significant difference was demonstrated in the speed of onset or duration of the block. Carbonated lidocaine gave an improved motor block and showed a trend towards giving fewer missed segments than lidocaine hydrochloride.

摘要

20名接受标准硬膜外麻醉的患者被随机分配,分别接受20毫升1.73%的碳酸利多卡因或2.0%的盐酸利多卡因,二者均含有1:200,000的肾上腺素。一名不知道所使用溶液的观察者测量起效速度、阻滞质量和作用持续时间。在起效速度或阻滞持续时间上未显示出显著差异。碳酸利多卡因产生了更好的运动阻滞效果,且与盐酸利多卡因相比,出现阻滞节段遗漏较少的趋势。

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2
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Comparison of lidocaine CO2, two per cent lidocaine hydrochloride and pH adjusted lidocaine hydrochloride for caesarean section anesthesia.利多卡因二氧化碳、2%盐酸利多卡因及pH值调整后的盐酸利多卡因用于剖宫产麻醉的比较。
Can J Anaesth. 1990 Apr;37(3):333-6. doi: 10.1007/BF03005585.
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