Mora F, Avrith D B, Rolls E T
Brain Res Bull. 1980 Mar-Apr;5(2):111-5. doi: 10.1016/0361-9230(80)90181-1.
It was found that neurons in the posterior orbitofrontal cortex, area 13, of the rhesus monkey were activated from self-stimulation electrodes (in 142 of 168 possible instances), and that neurons in the anterior orbitofrontal areas were much less likely to be activated from the self-stimulation electrodes (in only 28 of 177 possible instances). This activation of neurons in the posterior orbitofrontal cortex was found mainly from self-stimulation sites in the nucleus accumbens septi, lateral hypothalamus, and the orbitofrontal cortex itself. In a second investigation the orbitofrontal cortex was mapped for self-stimulation, and it was found that self-stimulation occurred in the posterior orbitofrontal area. These results implicate the posterior or caudal orbitofrontal cortex, mainly area 13, but not the more anterior orbitofrontal areas, in self-stimulation.
研究发现，恒河猴眶额皮质后部13区的神经元可被自刺激电极激活（在168个可能的实例中有142个），而眶额皮质前部的神经元被自刺激电极激活的可能性要小得多（在177个可能的实例中只有28个）。眶额皮质后部神经元的这种激活主要来自伏隔核、外侧下丘脑和眶额皮质自身的自刺激位点。在第二项研究中，对眶额皮质进行了自刺激定位，发现自刺激发生在眶额皮质后部区域。这些结果表明，自刺激与眶额皮质后部或尾侧，主要是13区有关，而与更靠前的眶额皮质区域无关。
