硝普钠单独及与筒箭毒碱合用的神经肌肉阻滞作用。

Neuromuscular blocking action of sodium nitroprusside alone and with d-tubocurarine.

作者信息

Diwan P V, Sharma P L, Varma Y S

出版信息

Eur J Pharmacol. 1980 May 2;63(2-3):183-5. doi: 10.1016/0014-2999(80)90442-2.

DOI:10.1016/0014-2999(80)90442-2

Abstract

The effect of sodium nitroprusside (SNP) per se on neuromuscular transmission and its effect on the action of d-tubocurarine (d-Tc) was studied in rabbits and rats. SNP produced a dose-dependent neuromuscular block which was not significantly antagonized by physostigmine. The tetanic response to nerve stimulation was not affected. Pretreatment with SNP significantly increased the intensity and the duration of action of d-Tc. The probable mechanism involved in SNP-induced neuromuscular blockade is discussed.

摘要

研究了硝普钠（SNP）本身对神经肌肉传递的影响及其对d -筒箭毒碱（d - Tc）作用的影响，实验对象为家兔和大鼠。SNP产生剂量依赖性神经肌肉阻滞，新斯的明对其无明显拮抗作用。对神经刺激的强直反应不受影响。SNP预处理显著增加了d - Tc作用的强度和持续时间。文中讨论了SNP诱导神经肌肉阻滞的可能机制。

相似文献

1

Neuromuscular blocking action of sodium nitroprusside alone and with d-tubocurarine.硝普钠单独及与筒箭毒碱合用的神经肌肉阻滞作用。

Eur J Pharmacol. 1980 May 2;63(2-3):183-5. doi: 10.1016/0014-2999(80)90442-2.

2

Effect of sodium nitroprusside on the biophase concentration of D-tubocurarine at the neuromuscular junction.硝普钠对神经肌肉接头处筒箭毒碱生物相浓度的影响。

Clin Exp Pharmacol Physiol. 1986 May;13(5):433-6. doi: 10.1111/j.1440-1681.1986.tb00922.x.

3

Nitroprusside and the duration of tubocurarine and pancuronium.硝普钠与筒箭毒碱和泮库溴铵的作用持续时间。

Anaesthesia. 1979 Nov-Dec;34(10):1005-9. doi: 10.1111/j.1365-2044.1979.tb06248.x.

4

Differing interactions between hexamethonium and tubocurarine, pancuronium or alcuronium at the neuromuscular junction.六甲铵与筒箭毒碱、泮库溴铵或阿库氯铵在神经肌肉接头处的相互作用差异。

Br J Anaesth. 1988 Oct;61(4):419-24. doi: 10.1093/bja/61.4.419.

5

Nitroglycerin and the neuromuscular blockade produced by gallamine, succinylcholine, d-tubocurarine, and pancuronium.硝酸甘油与加拉明、琥珀酰胆碱、d -筒箭毒碱和泮库溴铵产生的神经肌肉阻滞作用。

Anesth Analg. 1980 Feb;59(2):117-22.

6

Neuromuscular pharmacology in rat neonates: development of responsiveness to prototypic blocking and reversal drugs.新生大鼠的神经肌肉药理学：对典型阻断和逆转药物反应性的发育

Anesth Analg. 1992 Sep;75(3):361-71. doi: 10.1213/00000539-199209000-00008.

7

Effects of prostaglandins and indomethacin on neuromuscular blocking agents.

Can Anaesth Soc J. 1980 Mar;27(2):146-9. doi: 10.1007/BF03007777.

8

In vitro comparison between the neuromuscular and ganglion blocking potency ratios of atracurium and tubocurarine.阿曲库铵与筒箭毒碱在神经肌肉和神经节阻断效能比方面的体外比较。

Br J Anaesth. 1982 Dec;54(12):1307-11. doi: 10.1093/bja/54.12.1307.

9

The neuromuscular blocking activity of spectinomycin on the rat sciatic nerve-gastrocnemius muscle preparation.壮观霉素对大鼠坐骨神经-腓肠肌标本的神经肌肉阻滞活性。

Pharmacol Res Commun. 1986 May;18(5):451-7. doi: 10.1016/0031-6989(86)90165-7.

10

The effect of famotidine on neuromuscular transmission.法莫替丁对神经肌肉传递的影响。

In Vivo. 1991 Jan-Feb;5(1):53-5.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。