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[Effects of diacetoxyscirpenol on experimental candidiasis of mice].

作者信息

Salazar S, Fromentin H, Mariat F

出版信息

C R Seances Acad Sci D. 1980 Mar 31;290(13):877-8.

PMID:6771037
Abstract

A single injection of 4.5 mg/kg of diacetoxyscirpenol (a toxin synthesized by Fusarium) into Mice challenged by C. albicans, increases significantly the development of an experimental candidiasis. Suspensions of homogenized kidneys was spread on Sabouraud dextrose agar plates and the colonies of C. albicans were counted after 24 hrs incubation. The mean values were determined. Comparison of mean values calculated for kidneys from the Mice challenged with C. albicans and those challenged with C. albicans plus toxin gave highly significant results.

摘要

相似文献

1
[Effects of diacetoxyscirpenol on experimental candidiasis of mice].
C R Seances Acad Sci D. 1980 Mar 31;290(13):877-8.
2
[Pathogenicity of "Candida albicans" for normal mice and mice treated by the mycotoxin diacetoxyscirpenol (author's transl)].
Ann Microbiol (Paris). 1980 Jul-Aug;131B(1):39-46.
3
Experimental cryptococcosis in mice treated with diacetoxyscirpenol, a mycotoxin of fusarium.用镰刀菌的霉菌毒素二乙酰氧基雪腐镰刀菌烯醇处理的小鼠实验性隐球菌病
Sabouraudia. 1981 Dec;19(4):311-3. doi: 10.1080/00362178185380501.
4
Immunosuppressive activity of Fusarium toxins. Effects on antibody synthesis and skin grafts of crude extracts, T2-toxin and diacetoxyscirpenol.镰刀菌毒素的免疫抑制活性。粗提物、T2毒素和二醋酸雪腐镰刀菌烯醇对抗体合成及皮肤移植的影响。
Immunology. 1979 Jan;36(1):111-7.
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Effect of Fusarium toxins, T2-toxin and diacetoxyscirpenol on murine T-independent immune responses.镰刀菌毒素、T-2毒素和二醋酸藨草镰刀菌烯醇对小鼠非依赖T细胞免疫反应的影响。
Immunology. 1981 Nov;44(3):555-60.
6
Immunosuppressive effects of Fusarium extracts and trichothecenes: blastogenic response of murine splenic and thymic cells to mitogens.镰刀菌提取物和单端孢霉烯族毒素的免疫抑制作用:小鼠脾细胞和胸腺细胞对有丝分裂原的增殖反应
Proc Soc Exp Biol Med. 1979 Mar;160(3):302-11. doi: 10.3181/00379727-160-40439.
7
Inhibition of protein synthesis in Saccharomyces cerevisiae by the 12,13-epoxytrichothecenes trichodermol, diacetoxyscirpenol and verrucarin A. Reversibility of the effects.12,13-环氧单端孢霉烯族毒素木霉醇、二醋酸藨草镰刀菌烯醇和疣孢漆斑菌毒素A对酿酒酵母蛋白质合成的抑制作用。作用的可逆性。
J Antibiot (Tokyo). 1982 Jul;35(7):875-81. doi: 10.7164/antibiotics.35.875.
8
Nutritional effects on hematological and immunological responses of mice exposed to diacetoxyscirpenol (DAS).营养对暴露于二乙酰氧基雪腐镰刀菌烯醇(DAS)的小鼠血液学和免疫反应的影响。
Pathol Immunopathol Res. 1989;8(5-6):321-31. doi: 10.1159/000157160.
9
Effect of prenatal administration of T-2 toxin to mice.
Res Commun Chem Pathol Pharmacol. 1975 Apr;10(4):743-6.
10
Listeriosis in diacetoxyscirpenol-treated mice.双乙酰镳草镰刀菌烯醇处理小鼠中的李斯特菌病
Am J Vet Res. 1987 Oct;48(10):1516-9.

引用本文的文献

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Taxonomy, biology, and clinical aspects of Fusarium species.镰刀菌属物种的分类学、生物学及临床方面
Clin Microbiol Rev. 1994 Oct;7(4):479-504. doi: 10.1128/CMR.7.4.479.
2
Inhibition of mitogen-induced blastogenesis in human lymphocytes by T-2 toxin and its metabolites.T-2毒素及其代谢产物对人淋巴细胞有丝分裂原诱导的母细胞化的抑制作用。
Appl Environ Microbiol. 1985 Jun;49(6):1523-6. doi: 10.1128/aem.49.6.1523-1526.1985.