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婴儿意外摄入格列本脲:临床及脑电图表现

Accidental glibenclamide ingestion in an infant: clinical and electroencephalographic aspects.

作者信息

Pavone L, Mollica F, Musumeci S, Marino S, Pampiglione G

出版信息

Dev Med Child Neurol. 1980 Jun;22(3):366-71. doi: 10.1111/j.1469-8749.1980.tb03717.x.

Abstract

The clinical and EEG features of an infant during and after a severe episode of glibenclamide-induced hypoglycaemia are reported, with a 12-month follow-up. The very few cases reported in the literature, together with the present report, suggest that the neurological sequelae of severe hypoglycaemia resulting from ingestion of this drug are due to more patchy involvement of the central nervous system than would be expected from experimental work on hypoglycaemia.

摘要

报告了一名婴儿在严重的格列本脲诱导的低血糖发作期间及之后的临床和脑电图特征,并进行了为期12个月的随访。文献中报道的极少数病例以及本报告表明,摄入该药物导致的严重低血糖的神经后遗症是由于中枢神经系统受累更为散在,这超出了低血糖实验研究的预期。

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