Cantos de la Casa A, García Curiel A, Gómez Fernández M V, Arroyo Trillo A, Díaz Sánchez J A, Dueñas P
Med Clin (Barc). 1980 Jul 15;75(3):104-8.
Pseudomonas infections continue to be an important problem in the hospital environment. Serious infections are always invariably associated with severe underlying conditions or with diminished host resistance. The increasingly resistance of strains and hospital epidemics favour the organism prevalence. During 1978, Pseudomonas aeruginosa was isolated in 154 cultures from a variety of biological samples in the hospital. Tests of biochemical identification, serological typing, and typing by pyocine production were carried out. Susceptibility to aminoglycosides and beta-lactamic antibiotics was also tested. Serological study demonstrated a higher incidence of 4 and 11 serotypes; 69.4 percent corresponded to type I when typing by pyocine production was carried out. No relationship between serotypes and pyocine-types has been found. Ticarcillin showed a greater activity than carbenicillin (minimal inhibitory concentration less than or equal to 16 micrograms/ml). Amikacin, tobramicin, sisomicin and gentamicin inhibited 83.7 percent, 73.6 percent, 70.7 percent and 69.4 percent of the isolated strains, respectively.
假单胞菌感染在医院环境中仍然是一个重要问题。严重感染总是与严重的基础疾病或宿主抵抗力下降相关。菌株耐药性的增加和医院感染流行有利于该菌的传播。1978年期间，从医院各种生物样本的154份培养物中分离出铜绿假单胞菌。进行了生化鉴定、血清学分型以及通过绿脓菌素产生进行分型的试验。还测试了对氨基糖苷类和β-内酰胺类抗生素的敏感性。血清学研究表明血清型4和11的发生率较高；通过绿脓菌素产生进行分型时，69.4%对应于I型。未发现血清型与绿脓菌素型之间的关系。替卡西林比羧苄西林活性更强（最低抑菌浓度小于或等于16微克/毫升）。阿米卡星、妥布霉素、西索米星和庆大霉素分别抑制了83.7%、73.6%、70.7%和69.4%的分离菌株。
