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[铜绿假单胞菌培养物的抗菌谱以及血清型和毒力的比较研究]

[Comparative study of the antibiograms as well as serotype and virulence of Ps. aeruginosa cultures].

作者信息

Sobolev V R, Vlasova I V, Solov'eva V E, Bogdanova L F, Smirnova N E

出版信息

Antibiotiki. 1975 Jun;20(6):529-32.

PMID:817653
Abstract

Seven antibiotics, such as gentamycin, kanamycin, streptomycin, polymyxin M, carbenicillin, tetracycline and rifampicin were studied with respect to their effect on 260 strains of Ps. aeruginosa isolated from various sources within 1945-1971. Gentamycin and polymyxin M proved to be most active in vitro. Carbenicillin showed moderate activity. The sensitivity levels of the cultures of Ps. aeruginosa isolated from various sources within 30 years were identical. Serological typing of 59 cultures of Ps. aeruginosa was performed and their virulence was studied in parallel with their antibiotic sensitivity testing. No correlation between the antibiograms, serotypes and virulence of Ps. aeruginosa was found.

摘要

对庆大霉素、卡那霉素、链霉素、多粘菌素M、羧苄青霉素、四环素和利福平这七种抗生素,就其对1945年至1971年期间从各种来源分离出的260株铜绿假单胞菌的作用进行了研究。结果表明,庆大霉素和多粘菌素M在体外活性最强。羧苄青霉素显示出中等活性。30年内从各种来源分离出的铜绿假单胞菌培养物的敏感性水平相同。对59株铜绿假单胞菌培养物进行了血清学分型,并在进行抗生素敏感性测试的同时研究了它们的毒力。未发现铜绿假单胞菌的抗菌谱、血清型与毒力之间存在相关性。

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