Herzog S, Rott R
Med Microbiol Immunol. 1980;168(3):153-8. doi: 10.1007/BF02122849.
Borna disease (BD) virus from infected brain tissue of horses or rabbits could be grown in embryonic brain cells from rabbits or rats with high virus yields. The cells became persistently infected and could be subcultivated without loss of infectivity. Cocultivation of infected rabbit brain (ERB) cells with GMK-, Vero-, or MDCK-cells led to persistently infected cell lines. BD virus grown in MDCK cells after cocultivation became adapted to this cell type and could be used directly for further infection of MDCK cells.
从感染的马或兔脑组织中分离出的博尔纳病（BD）病毒，可在兔或大鼠的胚胎脑细胞中大量增殖。这些细胞会持续受到感染，并且能够传代培养而不丧失感染性。将感染的兔脑（ERB）细胞与GMK细胞、Vero细胞或MDCK细胞共同培养，可得到持续感染的细胞系。共同培养后在MDCK细胞中生长的BD病毒适应了这种细胞类型，可直接用于进一步感染MDCK细胞。
